Searchable abstracts of presentations at key conferences in endocrinology

ea0019p203 | Growth and development | SFEBES2009

Human fetal mesenchymal stem cells can differentiate into white and brown adipocytes, and reveal a role for ERRα in human UCP1 expression

Morganstein D , Wu P , Fisk N , White R , Parker M

Adipocytes have a key role in obesity and precursor cells can differentiate into white or brown adipocytes, with different metabolic functions. However the process by which stem cells commit to these lineages, and the factors that distinguish white adipogenesis from brown, are poorly understood.Fetal mesenchymal stem cells (fMSCs) can differentiate into adipocytes, but neither the regulation of this process, nor the phenotype differentiated cells has bee...